PV Bulletin

Filters should be used during the administration of Parenteral Nutrition for patients in all care settings DSI/2026/011

Administration of parenteral nutrition without a filter has been associated with fatal incidents, including embolism.

Primary source: Filters should be used during the administration of Parenteral Nutrition for patients in all care settings

PV Impact Brief

Urgency: HighConfidence: high

What changed

Healthcare professionals are now required to use integrated or add-on filters when administering parenteral nutrition in all care settings.

Why it matters

Failure to use filters during the administration of parenteral nutrition has been linked to severe adverse incidents, including fatal embolisms, highlighting a critical safety issue in patient care.

Action needed

Update local protocols to ensure parenteral nutrition is administered with filters in compliance with the new requirements.

Relevant for
Regulatory Intelligence LeadMedical Safety Lead
Processes impacted
Signal ManagementCountry Compliance
Owner

Regulatory Intelligence Lead

Review cadence

Review in the next regulatory intelligence cycle.

Evidence and confidence

Confidence: highSource updated: Sep 2, 2026

Full briefing

Practical implication

Update local protocols to ensure parenteral nutrition is administered with filters in compliance with the new requirements.

The MHRA issued a safety alert indicating that all parenteral nutrition solutions must be administered via a filter with a pore size no larger than 1.2μm to prevent adverse incidents, including fatalities.

What changed: Healthcare professionals are now required to use integrated or add-on filters when administering parenteral nutrition in all care settings.

Why it matters: Failure to use filters during the administration of parenteral nutrition has been linked to severe adverse incidents, including fatal embolisms, highlighting a critical safety issue in patient care.

Practical implication: Update local protocols to ensure parenteral nutrition is administered with filters in compliance with the new requirements.

View original source

  • Source: MHRA - Alerts, recalls and safety information: medicines and medical devices
  • Published at source: 2026-09-02T09:59:59.000Z
  • Discovered by monitor: 2026-09-02T22:01:06.529Z

Published from the regulator source ingestion pipeline after PV impact triage.

#Uk#Gov.uk#Safety Signal#Source-ingestion#Safety Signals#Regulator-monitor

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